Research library

Completed studies on training, performance diagnostics, nutrition and recovery – prepared for coaches and athletes: the result in plain language, the original numbers and a practical interpretation. Data source: ClinicalTrials.gov.

219 studies

2026

  • Post-training cold water immersion: no measurable effect on HRV, sleep and jump performance

    Randomized crossover study with NCAA Division I athletes from volleyball, American football and cross-country: two weeks each with five cold baths per week or without. HRV and sleep via WHOOP band, recovery questionnaires, and countermovement and drop jumps were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2026
  • Internal rotation deficit in cricket fast bowlers: movement control plus mobilization versus stretching

    Randomized, assessor-blinded study with 50 male cricket fast bowlers (aged 18–45) with shoulder pain and an internal rotation deficit over 10°: six weeks of Mulligan mobilization plus movement control training or plus stretching and isometrics, three times per week.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2026
  • Single PRP injection for chronic jumper's knee: no apparent advantage over saline after 32 weeks

    Randomized, participant-blinded study with 29 adults (aged 18 to 65) with patellar tendon pain lasting more than three months despite physiotherapy: one ultrasound-guided injection of 5 ml PRP or saline, with 32 weeks of follow-up using questionnaires and ultrasound.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2026
  • A single PRP injection for hip labral tears: patient ratings after six months

    Single-arm study from the University of Utah with 28 analyzed adults aged 18 to 49: a single injection of leukocyte-poor platelet-rich plasma into the hip joint after failed conservative treatment. How did patients rate their hip after six months?

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2026
  • Post-exercise photobiomodulation of the thigh muscles in special forces soldiers

    Randomized, sham-controlled study with 25 trained soldiers: three laser treatments per week on the front of the thighs after strength and conditioning sessions, for three weeks. Outcomes included jump performance, muscle soreness, isokinetic strength and sleep and heart rate from a ring.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2026
  • Eight weeks of hip strength training in female handball players: throwing velocity, hip strength and jumps

    Randomized study by Istanbul University with 40 female handball players aged 15 to 19: hip strengthening with resistance bands three times a week for eight weeks in addition to training versus usual training. Primary outcomes: throwing velocity, throwing accuracy and isokinetic hip strength.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2026
  • Short-term sleep loss and arterial stiffness in aerobically active and inactive adults

    Randomized crossover study with 24 healthy adults (aged 18–39), 12 aerobically active and 12 inactive: three days of normal sleep and three days with 30% less time in bed in random order. The primary outcome was pulse wave velocity as a measure of arterial stiffness.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2026
  • Minimally invasive water-jet tenotomy for chronic tennis and golfer's elbow

    Prospective single-arm observational study with 29 adults: ultrasound-guided tenotomy at the inner or outer elbow with the TenJet system after at least 3 months of unsuccessful conservative care. Pain and elbow function were tracked over 12 months.

    Observational study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2026
  • Blood flow restriction plus physiotherapy versus physiotherapy alone for tennis elbow

    Randomized Cleveland Clinic Akron General study with 41 adults aged 18 to 70 with tennis elbow: six physiotherapy visits with or without exercises under blood flow restriction. The primary outcome was the PRTEE symptom questionnaire after 12 months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2026
  • Digital twin in strength training: sprint and jump changes after app-supported leg training

    Single-arm intervention study with 23 healthy, resistance-trained adults (aged 20–40): twice-weekly self-directed training of the knee-stabilizing muscles logged in an iOS app. Stop-and-go running, 20 m sprint, countermovement and squat jumps were measured.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2026
  • Personal pain coach after surgery for sports injuries

    Randomized study with 148 adolescents and adults before orthopedic surgery for a sports injury: pain coaching in person, via telehealth, or standard care. Outcomes were pain intensity, opioid use, sleep and physical function up to three months after surgery.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2026
  • Movement screening and injuries in amateur rugby players over one season

    Prospective cohort study with 20 male amateur rugby players from the Fédérale 3 division: FMS test at the start of the season, then recording of all time-loss injuries for up to 7 months.

    Observational study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2026
  • Fitness tracker with and without a motivational group: effects on steps and sitting time

    Randomized three-arm study at National Chung Hsing University with 75 adults aged 18 to 64: one month of a Garmin tracker with motivational support via the LINE messenger app, tracker alone, or no device. Steps per day and sitting time were measured; sleep quality was also planned.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2026
  • Mental landing practice in volleyball: motor imagery alone or in a group

    Randomized study with 30 female volleyball players aged 15 to 25: motor imagery of correct landing in individual or group format versus a control group without training. Outcomes were joint angles at ground contact after jumping and cognitive tests after twelve weeks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2026
  • Mental fatigue, mindfulness and endurance: treadmill graded test after 30 minutes of a Stroop task

    Randomized crossover study with 90 athletes (aged 18 to 25): before a treadmill graded test they completed 30 minutes of a mentally fatiguing or an easy colour-word task. Groups with high, intermediate and low mindfulness were compared.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 03/2026
  • Pioglitazone and glucose oxidation during endurance exercise at simulated altitude

    Randomized, double-blind crossover study by the US Army Research Institute with active men: 5 days of pioglitazone or placebo, then 80 minutes on a treadmill in a hypobaric chamber at about 4300 m with 145 g glucose. 7 participants were analyzed.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 03/2026
  • Probiotic over 3 months in professional dancers: inflammatory markers, endocannabinoids and fatigue

    Randomized, triple-blind study from the Poznań University of Physical Education with professional dancers: a daily probiotic (L. helveticus R-0052 and B. longum R-0175) or placebo for 3 months. Blood markers and fatigue, sleep, stress coping and digestion were assessed.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2026
  • Electrical stimulation plus eccentric training after ACL reconstruction: strength symmetry, landing mechanics and cartilage

    Double-blind randomized trial by the University of Michigan (MiACLR) with 135 enrolled patients aged 14 to 45: 8 weeks each of high-intensity electrical stimulation and heavy eccentric leg press versus the same treatments at low intensity. Follow-up to 18 months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2026
  • Physiotherapy, shockwave and photobiomodulation for Achilles tendinopathy in runners: three-month pilot study

    Randomized pilot study with 46 runners (aged 18 to 65, at least 10 miles per week before injury) with mid-portion Achilles tendinopathy: physiotherapy alone, plus shockwave, or plus shockwave and light therapy. Outcomes at three months: VISA-A, calf raises to fatigue, tendon cross-sectional area.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2026
  • Nerve mobilization plus balance training for chronic ankle instability

    Randomized study with 36 adults (aged 20–50) with chronic ankle instability: 12 sessions of balance training alone or combined with a neurodynamic sliding technique for the common peroneal nerve. Pressure pain thresholds, nerve mobility, balance and function were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2026
  • Shockwave therapy plus Silbernagel programme versus training alone for Achilles tendinopathy

    Randomized study with 47 adults (aged 18 to 60) with unilateral Achilles tendinopathy: twelve weeks of a daily Silbernagel heel-raise programme with or without four sessions of low-energy focused shockwave therapy. Outcomes at 26 weeks: VISA-A, pain and tendon structure on ultrasound.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2026
  • Added genicular nerve block in ACL surgery: no significant reduction in opioid use

    Double-blind randomized trial in 192 adults undergoing outpatient ACL reconstruction: standard nerve blocks with or without an additional block of the genicular nerves. The primary outcome was opioid use in the first 24 hours.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2026

2025

  • Gait measurement in children: ActiGraph sensors compared with lab systems

    Prospective observational study with 87 healthy children and adolescents in three age groups (3–5, 6–11, 12–17 years). Hip- and wrist-worn ActiGraph sensors were compared in the lab with a GAITRite walkway and APDM sensors, followed by a wear period at home.

    Observational study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2025
  • Phone versus in-person follow-up after surgery in sports medicine

    Randomized study with 90 adults after surgery at a sports medicine clinic: follow-up visits at 6 weeks, 12 weeks and 6 months by phone or in person. The primary outcome was physical and mental health (PROMIS) at six months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2025
  • Beetroot extract in rugby players: acceleration, sprint, Bronco test and maximal strength

    Non-randomized, blinded crossover study by Universidad Nacional de Colombia with 10 rugby players: three days of waffles with 6 mmol nitrate from beetroot extract or placebo, followed by a 40 m sprint, Bronco test, squat, bench press and fatigue rating.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2025
  • Cautionary or reassuring back messages before the deadlift in military cadets

    Cluster-randomized study with 903 enrolled cadets aged 17 to 26: just before the deadlift test, a message about injury risk, one about spinal resilience, or none. Maximum weight lifted, beliefs about the back and self-confidence were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2025
  • Whole-body photobiomodulation in professional footballers: soreness, creatine kinase and jump performance after muscle-damaging training

    Quadruple-blind randomized study with 30 male professional footballers from a Brazilian club: whole-body LED irradiation before or after an intense strength session, or sham irradiation. Creatine kinase, soreness, knee extension strength and jump heights were measured up to 72 hours afterwards.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2025
  • Subthreshold aerobic exercise or stretching after sport-related concussion in adolescents

    Randomized trial from the University at Buffalo with 113 adolescents aged 10 to 18 within ten days of a sport-related concussion: daily aerobic exercise at 80% of threshold heart rate or daily stretching. The outcome was time to physician-confirmed recovery.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 10/2025
  • Sex hormones and neuromuscular control across the menstrual cycle and under hormonal contraception

    Prospective cohort study at UT Southwestern Medical Center with 102 people aged 18 to 39: 61 women with natural cycles, 30 using hormonal contraception, 11 men. Stretch and flexion reflexes, H-reflex, muscle twitch, force steadiness and cortical excitability by transcranial magnetic stimulation were measured.

    Observational study · ClinicalTrials.gov · Registerergebnisse / Registry results · 10/2025
  • Physical-cognitive video game training for older adults: attention and memory

    Randomized, blinded study with 49 healthy adults (aged 55–80): eight weeks of "Body-Brain Trainer", an exercise video game with adaptive cognitive tasks, or a control group using learning and logic apps. Attention, working memory, blood pressure, balance and EEG were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 09/2025
  • Decision aid for returning to contact sport after concussion in adolescents

    Non-randomized pilot study by Seattle Children's Hospital with 110 enrolled adolescents aged 11 to 17 or parents: usual care or an added decision aid on sport participation after concussion. Regret, decisional conflict, engagement and physical activity were measured.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 09/2025
  • Cold or warm water immersion after muscle-damaging jumps: no clear recovery advantage

    Randomized study with 30 healthy women (aged 18–35): after 5 × 20 drop jumps they underwent two 5-minute immersions in cold (10 °C) or warm (40 °C) water, or sat for 12.5 minutes. Maximal strength, soreness, swelling, creatine kinase, temperatures and muscle oxygenation were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 09/2025
  • Moderate cycle training versus light training with stretching: effects on learning and fitness in older adults

    Randomized, double-blind study with 122 inactive adults aged 55 to 80: 24 weeks of supervised moderate-intensity cycling or light cycling plus stretching, three times per week each, plus an acute comparison of single sessions. Outcomes were spatial learning, brain connectivity and VO2peak.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2025
  • Single yoga session, walking or rest: cognition and stress in inactive stressed adults

    Randomized study by the University of Illinois with 71 inactive adults aged 18 to 45 with anxiety symptoms: 30 minutes of sun salutations, treadmill walking at 50 to 70 percent of maximum heart rate, or seated rest. Primary outcome: working memory in the n-back test.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2025
  • Jump training and bone markers in female runners with a controlled energy deficit

    Randomized crossover study by Virginia Tech with 14 female runners: two five-day phases of reduced energy intake at 30 kcal per kg fat-free mass and daily treadmill running, once with an added 5 × 10 jumps. Blood markers of bone formation and resorption and hormones were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2025
  • Balance and hop tests under dual-task conditions in athletes after leg injury

    Cross-sectional comparison by Istanbul University with 39 high school and university athletes aged 14 to 30 from basketball, volleyball and football: previously injured on one leg or uninjured. Single-leg stability and three hop tests were assessed, alone and with an added cognitive task.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2025
  • Blood flow restriction training versus conventional resistance training in early ACL rehab

    Randomized pilot study by Abasyn University Peshawar with 32 people after ACL reconstruction: eight weeks of standard rehab with light leg training, 16 per group with or without blood flow restriction. Assessor-blinded.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2025
  • Pre-season dynamic balance and ankle injuries in high school and college athletes

    Prospective cohort study with 377 athletes aged 14 to 24 from various sports: Star Excursion Balance Test and Functional Movement Screen before the season, followed by recording of all ankle injuries. 59 sustained an ankle injury.

    Observational study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2025
  • Plantar fasciitis: strengthening versus stretching added to physical therapy

    Randomized, triple-blinded trial with 84 adults with plantar fasciitis: home program of strengthening or stretching exercises, each added to conservative physical therapy. Worst pain, morning pain and gait parameters were measured over three months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2025
  • Hyaluronic acid with sorbitol for overuse knee pain in recreational athletes

    Single-arm study from Mexico with 64 recreational athletes aged 30 to 55 with knee pain for over 3 months: injections of Synolis VA (hyaluronic acid with sorbitol), follow-up at 15 days, 3 and 6 months using the KOOS and IKDC questionnaires.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2025
  • Shockwave, laser or both added to physiotherapy for Achilles tendinopathy

    Randomized four-arm trial with active-duty US service members aged 18 to 64 (48 consented, 46 randomized) with mid-portion Achilles tendinopathy: physiotherapy alone, plus photobiomodulation, plus shockwave or plus both over three weeks. Measured: VISA-A, LEFS, pain and further function and ultrasound measures up to six months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2025
  • Mirabegron and cold-water tolerance: no apparent effect on the fall in core temperature

    Randomized, double-blind crossover study at Indiana University with 17 enrolled, regularly exercising adults (18–40 years): a single 100 mg dose of mirabegron or placebo before a progressively colder water immersion. The context is cold protection for Navy divers.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2025
  • Neck strengthening and head acceleration in youth soccer players

    Randomized study from the University of Michigan with soccer players aged 13 to 19: 12 weeks of supervised strength training twice a week, with or without intensive neck training. Head acceleration during direct impacts and simulated body checks was measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2025
  • Peanuts or carbohydrate snacks as a calorie surplus for muscle gain

    Randomized Virginia Tech study with 33 women and men (18 to 40 years) experienced in strength training: 10 weeks of supervised strength training three times a week plus an extra 500 kcal daily as a peanut snack or a peanut-free high-carbohydrate snack. Body mass and lean mass by DXA were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2025
  • Photobiomodulation for chronic plantar fasciitis: somewhat higher function scores with laser, similar pain – no between-group test

    Single-blind randomized trial in a military health system: 71 enrolled adults with plantar fasciitis lasting at least three months received nine laser sessions or a sham treatment over three weeks, each on top of usual care.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2025
  • Beta blocker esmolol during cycling: leg muscle oxygen saturation in younger and older women

    Randomized, blinded crossover study with 30 enrolled healthy women, premenopausal (18 to 35) or postmenopausal (55 to 70): cycling at moderate and heavy intensity under esmolol or saline. How did oxygen saturation in the working muscle respond?

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2025
  • Individually tailored digital program to increase activity in inactive Latina adolescents

    Randomized trial (Chicas Fuertes) from the University of California, San Diego, with 160 inactive Latina girls aged 13 to 18: counseling session, individually tailored website, text-message goal setting, Instagram and Fitbit versus Fitbit alone. Main outcome: moderate-to-vigorous activity at six months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2025
  • Photobiomodulation with static magnetic field for tennis elbow: placebo-controlled trial

    Randomized, quadruple-blinded trial with 50 adults (18 to 50 years) with tennis elbow: six treatments over three weeks with a light therapy plus static magnetic field device or identical sham treatment. Pain, function, grip strength and the inflammatory marker TNF-α were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2025
  • Oral contraceptives and injuries in college athletes: fewer time-loss injuries observed, but not randomized

    Non-randomized study with 73 basketball, soccer and volleyball players (aged 18 and older): 31 took a combined pill for one year, 42 used no hormonal contraception. The primary outcome was time-loss injuries; relaxin, knee ligament laxity and landing mechanics were also assessed.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2025
  • Targeted neuromuscular training, standard physiotherapy or home program before return after ACL reconstruction

    Randomized Mayo Clinic study with 150 athletes aged 13 to 30 from sports with jumping and cutting: six weeks of final-stage rehab in three variants after ACL reconstruction. How many then suffered a second ACL tear?

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2025
  • Erythropoietin during heavy training: blood values, running performance and fat metabolism

    Single-arm study with 8 recreationally active adults: epoetin alfa three times per week for 4 weeks during an intense training program. Outcomes were hemoglobin, 5 km treadmill time and fat oxidation under load.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2025
  • Landing mechanics, hip control and muscle activity in jumper's knee in volleyball and basketball

    Case-control study with 34 volleyball and basketball players aged 18 to 40: 17 with patellar tendon pain and 17 pain-free players matched for sex, age and body size. Joint angles in countermovement jump and step-down, hip control and biceps femoris EMG were measured.

    Observational study · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2025
  • Cruciate ligament reconstruction: two absorbable fixation screws compared

    Randomized, assessor-blinded multicentre study with 140 adults (aged 18–75) in China: cruciate ligament reconstruction using the new Biosure Regenesorb screw or its predecessor BIOSURE HA. The main outcome was the Lysholm score at 12 months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 03/2025
  • Multi-day nitrate intake against mountain sickness and for endurance in hypoxia

    Bangor University, crossover with 23 healthy adults: six days each of a nitrate-rich beetroot shot or nitrate-depleted placebo, then six hours of hypoxia to assess mountain sickness and an endurance test to exhaustion at a simulated 3225 m.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2025
  • PRP injections after acute ACL tear: course of inflammatory markers in the knee joint until surgery

    Randomized phase 2 study with 24 patients aged 14 to 40 with a fresh ACL tear and bone bruise: joint aspiration alone or aspiration plus two injections of leukocyte-poor platelet-rich plasma before reconstruction. Ten inflammatory messengers in the joint fluid were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2025
  • Practice structure with limited full contact: head impacts in football players aged 11 to 14

    Non-randomized pilot study from Wake Forest University with 106 participants – youth players, coaches, parents and league officials: sensor mouthguards measure head impacts in practice, first under usual practice, then with the jointly developed COACH practice structure.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2025
  • Acute combined endurance and resistance exercise and task-switching ability

    Randomized study at National Taiwan Normal University with 78 adults aged 21 to 28: 35 minutes each of combined endurance-resistance exercise, endurance exercise only, or reading. Afterwards, a task-switching test with response times, plus lactate before, during and after the session.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2025
  • Coconut water versus electrolyte solution for fluid intake in adolescent athletes

    Randomized, double-blind study from the Universidad de Colima (Mexico) with 34 male students aged 12 to 17: four weekly endurance sessions with coconut water or electrolyte solution (Electrolit). Hydration status was assessed by urine specific gravity, body water by bioimpedance and weight loss.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2025
  • Motor imagery with active or sham tDCS for learning a walking obstacle course

    Randomized, double-blind pilot study (ELLMITS) with 38 healthy adults: video-based motor imagery with 20 minutes of active tDCS over the prefrontal cortex, the same imagery with sham stimulation, or a neutral video. Course time, brain activity (fNIRS) and feasibility were measured over one week.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2025
  • Kinesio tape on the upper trapezius and lower trapezius activity in healthy adults

    Randomized, triple-blind crossover study with twenty-two adults with healthy shoulders: arm raising without tape, with inhibitory kinesio tape and with sham tape, each without load and with 2.3 kg. Muscle activity was measured with high-density EMG.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2025
  • Naproxen gel versus diclofenac gel and placebo for acute soft tissue injuries of the leg

    Randomized, double-blind phase 2 trial by Bayer with 76 adults: treatment of fresh sports-related soft tissue injuries of the leg or foot with 10% naproxen gel, 2.32% diclofenac gel or placebo. The main outcome was pressure tenderness over 72 hours.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2025
  • Mindfulness training and mental fatigue: a benefit only for time to exhaustion

    Randomized study with 53 athletes (aged 18–25): eight weeks of a mindfulness program or waitlist. Before and after, the researchers tested how much a fatiguing Stroop task impairs treadmill performance, response control and EEG signals.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2025
  • Ashwagandha extract and strength, wellbeing and recovery in female footballers

    Double-blind, placebo-controlled study with 30 sub-elite to elite female footballers: 28 days of 600 mg KSM-66 ashwagandha or a chickpea flour capsule daily. Jump performance, grip strength, medicine ball throw, perceived exertion, Hooper Index and perceived recovery were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2025

2024

  • Initial graft tension in ACL reconstruction and knee osteoarthritis after 15 years

    Randomized, triple-blind long-term study from Rhode Island Hospital: 90 active patients with ACL reconstruction at low or high graft tension, plus 60 uninjured controls. X-rays, knee questionnaires, stability and quality of life over up to 15 years.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2024
  • Blood flow restriction training before and after ACL reconstruction: quadriceps strength and muscle cross-section

    Randomized, triple-blinded study with patients aged 15 to 40 with a recent ACL tear: standard rehab plus blood flow restriction or plus a sham cuff, about 4 weeks before and up to 24 weeks after surgery. Strength, rate of torque development, muscle MRI and gait mechanics were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2024
  • Load-modification education or standard exercise for greater trochanteric pain syndrome (GLAM trial)

    Randomized trial by Ohio State University with 62 enrolled adults aged 18 to 70 with unilateral lateral hip pain: four weeks of standard exercise versus exercise plus education on avoiding tendon-loading postures. Primary outcomes: global change and pain.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2024
  • Exercise-induced hypoalgesia in knee extension: high versus low intensity

    Randomized study from the University of Central Florida with 60 pain-free adults (18 to 60 years): three sets of ten knee extensions at 75% or 30% of one-repetition maximum, or quiet sitting. Pressure pain threshold and conditioned pain modulation were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2024
  • Photobiomodulation helmet after sport-related concussion: pilot study on safety and course

    Randomized, single-blind pilot study by the manufacturer REGEnLIFE with 50 adults who sustained a concussion during sport: two 20-minute helmet treatments with light pulsed at 5 Hz or 10 Hz. How safe was the device, and how did symptoms develop?

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2024
  • Painful versus pain-free stretching and ice water: similar pressure pain thresholds at the foot

    Randomized crossover study at the University of Central Florida with 30 healthy adults (18–60 years): neck stretching into pain, pain-free stretching and hand ice water immersion, each four times for one minute. The primary outcome was pressure pain threshold between the first and second toes.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2024
  • Vascular function after HIIT in older men and postmenopausal women

    Non-randomized study from the University of Florida with 20 untrained adults aged 60 to 79: an 8-week control phase, then 8 weeks of remotely supervised home-based non-weight-bearing HIIT using arms and legs. Acute and long-term vascular responses were assessed.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2024
  • Occlusion training after ACL reconstruction: effects on muscle and bone mass

    Randomized study with 50 adults aged 18 to 35 after ACL reconstruction with a patellar tendon graft: standard rehab with or without blood flow restriction at 20% of maximal load. DEXA measurements of lean mass, bone mass and bone density over twelve weeks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2024
  • Short home exercise sessions for older adults with mild cognitive impairment: acceptability pilot

    Single-arm pilot study from the University of Bath with 21 memory clinic patients over 65: one short, equipment-free exercise session every morning and evening for 28 days. How well was it accepted – and did physical function change?

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 10/2024
  • Five-toed socks in chronic ankle instability: balance and reach

    University of Toledo: 53 active adults aged 18 to 30, 23 with unilateral ankle instability. Sway in single-leg stance with eyes open and closed and reach in the Star Excursion Balance Test were measured, all while wearing toe socks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2024
  • Bone-void filler at the harvest site after ACL reconstruction with patellar tendon: effect on anterior knee pain

    Randomized, unblinded trial from NYU Langone Health with 150 adults after ACL reconstruction with bone–patellar tendon–bone graft: harvest defect filled with autologous bone alone, autologous bone plus demineralized bone matrix, or plus calcium phosphate cement. KOOS, Kujala score and knee pain at twelve months were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2024
  • Blood flow restriction in shoulder training: effects on muscle mass and strength in untrained adults and pitchers

    Randomized, unblinded study with two cohorts: healthy untrained adults (16 per group) and collegiate baseball pitchers (19 and 18 started) trained the rotator cuff for eight weeks at 20% of maximal strength – with or without a cuff at 50% occlusion.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2024
  • Change in aerobic fitness and cognition in carriers and non-carriers of the ApoE e4 gene

    Prospective cohort study from National Taiwan Normal University with 159 adults aged 50 to 70: are fitness changes over 18 months linked to inhibitory performance on the Stroop task, and does the Alzheimer risk gene ApoE4 play a role?

    Observational study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2024
  • Neuromuscular training with real-time biofeedback in young female athletes: brain activity and landing technique

    Randomized, triple-blinded Emory University study with 93 female athletes aged 12 to 19: 6 weeks of neuromuscular training with real or sham biofeedback via AR glasses. Brain activity by fMRI and knee angles during lab and VR landings were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2024
  • Blood flow restriction training after ACL reconstruction in adolescents

    Non-randomized pilot study at Connecticut Children's Medical Center: 47 adolescents after ACL reconstruction, 33 of them with added BFR training in physiotherapy. Isometric quadriceps and hamstring strength and the Pedi-IKDC were measured at three months and at return to sport.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2024
  • Sensor and smartphone companion system for more everyday movement in older adults

    Randomized pilot study from Northeastern University: 46 inactive, overweight adults over 60 completed 16 weeks of supervised training, half of them with the "Companion" coaching system. Activity and sitting time were measured by accelerometer at 4 and 6 months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2024
  • Wearable sensor counts pitches in young baseball pitchers

    Single-arm feasibility study from the Children's Hospital of Philadelphia with 10 youth pitchers aged 8 to 14: an arm sensor was meant to detect every throw during a simulated game, compared with visual counting.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2024
  • Foot and ankle strengthening in distance runners: fewer injuries after one year, but without statistics

    Randomized trial at the University of São Paulo with 118 recreational runners (18–55 years, at least 20 km per week): eight weeks of foot and ankle training with a physiotherapist and an app, or stretching as a control. The primary outcome was the number of running-related leg injuries within one year.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2024
  • Longer or equal exhale: twelve weeks of slow breathing, HRV and anxiety

    Randomized trial from Vanderbilt University with 99 healthy adults (30 to 60 years): twelve weeks of daily slow yoga breathing, either with exhale longer than inhale or with equal phases. High-frequency heart rate variability and anxiety were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2024
  • Core stabilization training in adolescent footballers: kicking velocity, sprint and agility

    Non-randomized intervention study from Hacettepe University with 45 male youth footballers (12 to 14 years) from an academy in Gönyeli: eight weeks of core stabilization on top of football training or regular training only. Kicking velocity by radar, 20 m sprint and the 505 agility test were measured.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2024
  • Omega-3 (DHA) after concussion in college athletes: return to sport

    Randomized, double-blind study with 62 NCAA Division I athletes at East Carolina University: within 24 hours of a concussion they started taking 2200 mg DHA or placebo daily. Did athletes get back on the field faster?

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2024
  • Running style transition with biofeedback: foot strike and knee pain over one year

    Randomized, blinded study with 191 runners (aged 18–50, at least 12 miles per week) at West Point: transition away from heel striking with or without a shin-mounted accelerometer. Foot strike after training, at six months and at one year, plus injuries, were recorded.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2024
  • Landing technique and balance across a season in college athletes doing prevention training

    Single-arm field study at Northern Vermont University with NCAA Division III athletes (18 to 24 years) from soccer, volleyball and basketball: about ten minutes of prevention training at least four times a week, testing landing technique (LESS) and balance (BESS) at the start, middle and end of the season.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2024
  • Edible THC and endurance performance on the cycle ergometer: barely any difference from placebo

    Randomized crossover study in regular exercisers who habitually use cannabis (21–40 years): two 5 mg THC gummies or placebo before a cycling exercise protocol. Lactate, heart rate, VO2, RPE, time-trial mean power and time to exhaustion were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2024
  • Additional IPACK block after ACL reconstruction: opioid use and pain

    Randomized, single-blinded NYU Langone Health study with 102 adults (18 to 75 years) undergoing ACL reconstruction with a patellar tendon graft: adductor canal block alone or plus an IPACK block. Opioid use, pain up to day 7 and knee function at 6 months were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2024
  • One strength training session and the release of miR-1 from muscle: basic science study in untrained adults

    Single-arm intervention study with 38 untrained adults (aged 18 to 30, BMI below 25 or above 30): one session of leg press, squat, knee extension and lat pulldown at 80% of maximum. miR-1 in blood vesicles, muscle and fat tissue was measured before and 90 minutes after.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2024
  • Carbon fiber orthosis with medial or lateral wedge: effects on knee mechanics and function in healthy adults

    Randomized crossover pilot study with 20 healthy adults at the University of Iowa: walking and functional tests without a brace, with a carbon fiber ankle-foot orthosis, and with the orthosis plus a medial or lateral wedge. Outcomes included knee motion, knee moment, agility, pain and comfort.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2024
  • High or low training volume in subthreshold aerobic exercise after sport-related concussion

    Randomized study from the University at Buffalo with 60 adolescents aged 13 to 18: athletes with concussion and healthy controls did two weeks of aerobic exercise at 90% of their exercise threshold, at high or low volume. The outcome was who still had symptoms beyond four weeks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2024

2023

  • Behavioral activation for more everyday movement in older employees

    Randomized pilot study from Duke University with 26 employees aged 50 to 64: a movement-oriented behavioral activation group program (MOBA) immediately or after a waiting period. Outcomes were acceptability, physical performance, walking distance and activity behavior.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2023
  • Six months of high-dose omega-3 (EPA/DHA) in older adults: strength, body composition and inflammation markers

    Triple-blind randomized trial from Mayo Clinic: older adults took four capsules daily with a total of 3.4 g EPA and DHA or soybean oil placebo for six months. Leg strength, BMI, body fat, lean mass and the inflammation markers CRP and ESR were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2023
  • PRP injection for patellar tendinopathy: improvement in all groups, no demonstrated advantage

    Double-blind randomized phase 2 trial at the University of Wisconsin: 30 enrolled adults (18–39 years) with chronic jumper's knee who had not improved with physiotherapy. PRP injection, dry needling and a sham procedure compared over 52 weeks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 10/2023
  • Autologous blood therapy for jumper's knee: PRP alone or with IGF concentrate

    Randomized, double-blind pilot study with 14 physically active adults with patellar tendinopathy after failed rehab: PRP injection alone or PRP plus concentrated plasma containing IGF. The main outcome was the VISA-P score at six months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 10/2023
  • Esflurbiprofen patch for pain after acute sports injuries: placebo-controlled trial

    Double-blind, randomized phase 2 trial with 200 adults (18 to 60 years) with a fresh bruise, strain or sprain of an arm or leg after blunt trauma in sport: hydrogel patch with 165 mg esflurbiprofen or identical placebo patch. The main outcome was pain on movement at 72 hours.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 09/2023
  • Walking dose and pain sensitivity: three, five or ten treadmill sessions in one week

    Pseudo-randomized study with 41 healthy women (aged 18 to 40): 30 minutes of brisk treadmill walking three, five or ten times in one week, or rest as control. Pressure, heat and touch sensitivity were measured on forearm and calf.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2023
  • 16 weeks of whole-body EMS training: vascular function, fitness and blood values in healthy adults

    Randomized, double-blind study from the Mayo Clinic with 78 healthy adults: 16 weeks of training in an EMS suit with the device switched on or off. Outcomes included endothelial function, VO2max, blood lipids, muscle enzymes and well-being questionnaires.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2023
  • Fitness trackers and motivational interviewing for inactive adults: four approaches compared

    Randomized Colorado State University study with 40 inactive adults in four groups of ten: fitness tracker, six motivational interviewing sessions, both combined, or activity guidelines only. Twelve weeks, measured with questionnaires and accelerometers.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2023
  • Stiffness of a carbon fiber ankle-foot orthosis and its effect on gait mechanics

    Randomized crossover study at the University of Iowa with 20 healthy adults aged 18 to 45: walking without an orthosis, with a moderate-stiffness and with a stiff Malleo-Lok orthosis. Ankle stiffness, push-off power, joint moment as well as pain and comfort were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2023
  • Gait stability with a hands-free knee crutch and standard axillary crutches in a simulated foot injury

    Randomized crossover study at the University of Iowa with 21 healthy adults aged 18 to 45: walking without aids, with a walking boot only, with a hands-free crutch or with axillary crutches, each with and without a boot. The primary outcome was whole-body angular momentum as a measure of gait stability.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2023
  • Submaximal aerobic exercise after concussion in adolescents

    Randomized study from Boston Children's Hospital with 41 patients aged 14 to 21: 8 weeks of heart-rate-guided aerobic exercise on 5 days per week or usual care. Outcomes included symptoms, cerebrovascular response, heart rate and exercise volume.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2023

2022

  • Blood flow restriction in rehab after anterior cruciate ligament reconstruction

    Randomized study from Inova Health with 25 plus 20 patients after ACL reconstruction: standard physical therapy with or without a BFR cuff from the second week after surgery. Knee function, pain, strength, muscle girth and range of motion tracked to week 12.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2022
  • Single testosterone dose during simulated operational stress: performance, body composition and recovery

    Double-blind, randomized trial (OPS II) with 34 physically active men aged 18 to 35: a single 750 mg testosterone undecanoate or placebo injection before 20 days of in-patient simulated operational stress from exercise, sleep restriction and energy deficit. Load carriage time, jump, deadlift, Wingate, VO2peak and body composition were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 10/2022
  • Sport Education model in compulsory university PE: activity, motivation and physical literacy

    Cluster-randomized study from the Chinese University of Hong Kong with 410 students: 10 lessons following the Sport Education model or regular PE. Outcomes included activity by questionnaire and sensor, motivation, enjoyment and lesson structure.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2022
  • Kinesiology tape direction on the quadriceps: no effect on jumping and strength

    Randomized, blinded crossover study with 15 healthy adults (aged 18–35) with no taping experience: kinesiology tape on the quadriceps applied once from knee to hip and once from hip to knee. Vertical jump, single-leg triple hop, isokinetic torque and EMG were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2022
  • Sever's disease in young barefoot athletes: two heel braces compared

    Randomized study with 43 children (aged 8–14) from martial arts, dance, gymnastics or acrobatics with Sever's disease: Cheetah heel cup or X brace for three months. Pain at rest, in daily life and during sport was recorded, along with the child-specific foot questionnaire OxAFQ-C.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2022
  • Personalised blood flow restriction in ACL rehab: effect on knee and hip movement in one exercise session

    Non-randomized cross-sectional study with 40 adults: 20 people at least three months after ACL reconstruction and 20 healthy controls performed a rehab exercise with and without individually dosed blood flow restriction. Joint angles, joint moments, difficulty and discomfort were measured.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2022
  • Tennis elbow in general practice: physiotherapy with steroid or placebo injection versus wait-and-see

    Randomized, placebo-controlled study with 177 adults (aged 18–70) with recent tennis elbow: physiotherapy plus steroid injection, physiotherapy plus placebo injection, or wait-and-see. Self-rated treatment success was tracked over 52 weeks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2022
  • S-ibuprofen gel for muscle soreness: no significant advantage over a drug-free gel

    Randomized, quadruple-blind phase 2 trial by Aponia Laboratories with 251 healthy adults (18–55 years) with muscle soreness: 5% S-ibuprofen gel or drug-free vehicle gel. The primary outcome was pain relief with movement over 24 hours.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2022

2021

2020

  • Q-Collar in high school football: jugular compression and brain changes over a season

    Randomized study by Cincinnati Children's Hospital with 62 high school football players aged 14 to 19: one season with or without the Q-Collar. Head impacts were measured with helmet sensors and white matter changes with diffusion MRI.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2020
  • Biofeedback training against loading asymmetry after ACL reconstruction in young athletes

    Randomized trial from Virginia Tech with 40 people aged 14 to 21 after ACL reconstruction: twelve biofeedback squat sessions over six weeks versus an education program. Knee extension moment, ground reaction force and knee motion were measured during a stop-jump.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2020
  • Secukinumab for treatment-resistant rotator cuff tendinopathy: phase 2 trial against placebo

    Randomized, quadruple-blind phase 2 trial by Novartis with 96 patients aged 18 to 65 in whom painkillers and physiotherapy had failed: 300 mg secukinumab or placebo under the skin over 12 weeks, follow-up to week 24.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2020
  • Q-Collar in female soccer players: white matter changes over a season

    Non-randomized study with 72 female high school soccer players (14 to 19 years): one group wore the "Q-Collar" neck device during the season, the other did not. Head impacts were recorded by a sensor behind the ear, brain changes by diffusion MRI.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2020
  • Tau imaging in former professional American football players as a possible CTE marker

    Non-randomized phase 2 study by the manufacturer Avid Radiopharmaceuticals: PET scans with flortaucipir (tau) and florbetapir (amyloid) in 30 former NFL players and 11 former athletes from non-contact sports.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 09/2020
  • Ipratropium bromide to prevent exercise-induced asthma in endurance athletes: no results in the registry

    Planned randomized, quadruple-blind crossover study at the University of California, San Francisco (STAMINA) in endurance athletes: two puffs of ipratropium bromide or placebo before each exercise challenge to provoke exercise-induced asthma. 20 participants are reported as enrolled, but results are missing.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2020
  • Cetirizine and cycling time trial at simulated altitude: crossover study in active adults

    Randomized, double-blind crossover study from Indiana University with 13 active adults (8 analyzed): 8 km cycling time trial after 10 mg cetirizine in hypoxia, after placebo in hypoxia and after placebo in normal room air. Time-trial duration and blood histamine were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2020
  • More referees, fewer injuries? A field study in youth soccer

    Non-randomized crossover study in a youth league in Birmingham, Alabama: 49 teams of 8- to 11-year-olds each played one match with one referee and one with three. Injuries were counted when a child had to leave the field or needed adult attention.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2020
  • Active video games for inactive children: effects on weight, BMI, reaction time and self-perception

    Randomized pilot trial from Turkey with 106 physically inactive, technology-focused children (8 to 13 years): twelve weeks of Nintendo Wii active games in the lab versus a control group without games. Outcomes were weight, BMI, body fat, reaction times and self-perception.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2020
  • Interval cycling or balance exercise in older age: effects on fitness and motor brain activity

    Randomized crossover study from the US Department of Veterans Affairs: 33 older adults completed twelve weeks each of supervised interval cycling and stretching/balance training, followed by six months of home cycling. Outcomes were estimated VO2peak, TMS and fMRI measures.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2020
  • Gait, balance and cognitive tests for assessing concussion in high school athletes

    University of Arkansas pilot study with 327 football and soccer players aged 14 to 18: repeated ImPACT tests over one year in healthy players, plus gait analysis with dual task, the Y-Balance Test and a reaction test comparing healthy and recently concussed athletes.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2020
  • Remote ischemic conditioning of the arm and strength gains in wrist training

    Randomized, single-blind phase 1 study at Washington University with 34 healthy adults aged 18 to 40: eight sessions of ischemic conditioning with a blood pressure cuff or sham, combined with strength, driving-simulator and balance training. Primary reported outcome: wrist extensor one-repetition maximum.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2020
  • HIIT versus circuit training: low volume, different VO2max effect

    Randomized study with 42 recreationally active adults (aged 18–65): eight weeks of high-intensity interval training on a cycle ergometer or seven-station circuit training, each twice a week under supervision. VO2max and ventilatory threshold were measured in cardiopulmonary exercise testing.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2020
  • Soy versus whey protein matched for leucine during 12 weeks of resistance training

    Randomized, double-blind study with 61 recreationally active women and men aged 18 to 35: 12 weeks of resistance training plus 26 g soy or 19 g whey protein daily, both providing 2 g leucine. Who built more muscle?

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2020
  • Thrower's Ten shoulder strengthening in wheelchair and standing basketball players

    Single-group study from Hacettepe University: 13 wheelchair and 15 standing basketball players (all male professionals) trained for eight weeks with the Thrower's Ten program. Shoulder strength, grip strength, medicine ball throws and range of motion were measured at 8 and 12 weeks.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2020
  • Growth hormone around ACL surgery to prevent thigh strength loss

    Randomized, triple-blinded phase 2 trial by the University of Michigan with 20 men aged 18 to 35: somatropin or placebo twice daily from one week before to five weeks after ACL reconstruction. Primary outcome: knee extension strength at 26 weeks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2020

2019

  • Peer-led eating disorder prevention for female college athletes (Female Athlete Body Project)

    Cluster-randomized trial from Pennington Biomedical Research Center with 481 female athletes from university teams: the "Healthy Weight" prevention program led by peer athletes versus an information brochure with wait-list option. Eating disorder symptoms (EDE-Q), binge episodes and thin-ideal internalization were assessed over 18 months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2019
  • Calorie deficit and protein intake: five-day diet phases in lean, endurance-active men

    Randomized crossover study with 20 enrolled lean men (aged 19 to 30, at least 4 hours of endurance exercise per week): five days each of calorie deficit with 1.7 or 0.8 g protein per kg body weight, or energy balance, each with daily endurance exercise.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2019
  • Two stabilizing boots compared with a sports shoe: ankle range of motion and gait symmetry

    Randomized crossover study by the Institute for Biomechanics at ETH Zurich with 20 healthy adults aged 18 to 45: walking in a sports shoe, the VACOped and the Ortho Tri-Phase with randomized boot order. Ankle range of motion and step length symmetry were recorded.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2019
  • Protonics knee brace versus rubber cord training for anterior knee pain: similar improvements after four weeks

    Randomized, unblinded study at Loma Linda University with 43 adults (18–45 years) with patellofemoral pain: four weeks of hamstring resistance training with the Protonics brace or a sport cord. Pelvic tilt, pain, Kujala score and self-rated change were assessed.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2019
  • Platelet-rich plasma plus cast versus cast alone for acute lateral ankle sprain

    Randomized study from Mexico with 21 adults (18 to 60 years) with an acute grade 2 or 3 lateral ankle sprain: two weeks of lower-leg cast, with or without a single injection of 5 mL autologous PRP. Function scores and pain after six months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 10/2019
  • Kinesiology tape for tennis elbow: real tape, sham tape and exercise compared

    Randomized, double-blind study in adults (11 per group) with tennis elbow for less than 12 weeks: kinesiology tape plus exercise, sham tape plus exercise, or exercise alone. Pain, daily function and grip strength were measured after two and six weeks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 10/2019
  • Dehydration sensor in a wearable: accuracy of sweat loss measurement during running

    Validation study with 201 healthy adults (aged 18–50) in four age groups: while running they wore the Spectrophon Dehydration Body Monitor in a Samsung Gear S2 and a Gear Fit2. The number of readings deviating by more or less than 20% from weighed body mass loss was counted.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 10/2019
  • Q-Collar in young contact-sport athletes: white matter changes on MRI

    Randomized pilot study at Cincinnati Children's Hospital with 15 high school athletes aged 14 to 19 in contact sports: a season with or without the Q-Collar. Diffusion tensor imaging compared white matter measures at the start and middle of the season.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 09/2019
  • FIFA 11+ warm-up in adult female amateur soccer players: effects on sprint, agility and jumping

    Non-randomized pilot study at the University of British Columbia with 21 female amateur soccer players (18–45 years) from two teams: FIFA 11+ or the usual time-matched warm-up, three times per week over eight in-season weeks. Testers were blinded to group allocation.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 09/2019
  • Active versus seated video games: energy expenditure and eating in adolescents

    Randomized crossover study from Ottawa with 30 adolescents aged 13 to 17: one hour each of Kinect active gaming, seated Xbox gaming or rest, with a week in between. How much did they eat and burn afterwards?

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2019
  • Acute effect of a three-hour road or mountain bike ride on back pain and muscle tone

    Randomized crossover study at Universidad Europea de Madrid with 40 male amateur cyclists: three hours on a road bike (90 km) and three hours on a mountain bike (55 km), one week apart. Outcomes were low back pain, pressure pain threshold and tensiomyography of back and thigh muscles.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2019
  • Ischemic conditioning of the arm to enhance motor learning: how many cycles?

    Randomized, single-blind study from Washington University with 40 healthy 18- to 40-year-olds: three, four or five occlusion cycles on the upper arm or sham on seven weekdays, combined with balance, hand and sequence learning tasks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2019
  • Octacosanol in adolescent taekwondo athletes cutting weight: favorable end values, but no baseline data

    Randomized, double-blind study at Kosin University with 26 male taekwondo athletes (17–19 years) with at least three years of national competition experience: six days of octacosanol (20 mg twice daily) or placebo during rapid weight loss.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2019
  • Trunk-focused neuromuscular training against ACL risk in young female athletes

    Randomized, quadruple-blinded study with female school athletes in soccer, basketball and volleyball in Kentucky: neuromuscular training with lateral trunk perturbations versus sprint training of similar volume. 307 and 216 players were followed over 2 years.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2019
  • Recombinant growth factor rhPDGF-BB injection for chronic tennis elbow

    Randomized, double-blind, placebo-controlled phase II study at 6 centers with 100 adults (21 to 80 years): a single injection into the extensor carpi radialis brevis with placebo or 0.45, 0.75, 1.5 or 3.0 mg rhPDGF-BB. Pain, DASH, PRTEE and grip strength over 24 weeks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2019
  • Inspiratory muscle training in active men: effects on diaphragm activation, breathlessness and muscle oxygenation

    Randomized, single-blind study from the University of British Columbia with 25 recreationally active men aged 19 to 39: inspiratory muscle training versus sham training. Diaphragm EMG, scalene and sternocleidomastoid activity, Borg breathlessness and thigh oxygen extraction were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2019
  • Ten-week sleep programme for collegiate athletes with and without light technology

    Randomized study with 40 student athletes at the University of Arizona: a ten-week sleep programme with education, fitness tracker, daily sleep diary and text reminders, supplemented in one group by blue-blocking glasses and an LED light alarm. Sleep quality, insomnia, stress, depressive symptoms and quality of life were assessed.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2019
  • Dapagliflozin plus endurance training in inactive, overweight adults

    Randomized, placebo-controlled, triple-blind phase 2 study with 37 inactive adults aged 18 to 50 with BMI 25 to 45: twelve weeks of supervised endurance training four times a week plus dapagliflozin or placebo. Outcomes: VO2max, respiratory exchange ratio, citrate synthase, insulin sensitivity, fat-free mass.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 04/2019
  • Three grafts for ACL reconstruction compared over five years

    Randomized trial, blinded for patients and assessors, with 330 people aged 14 to 50: ACL reconstruction with patellar tendon, quadruple hamstring tendon or double-bundle technique. Quality of life, knee stability, re-ruptures and return to activity level over up to five years.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2019
  • Optical wrist heart rate monitors compared with ECG and chest strap

    Prospective Cleveland Clinic study with 50 healthy adults: each participant wore two of four wrist devices (Apple Watch, Fitbit Charge HR, Mio Fuse, Basis Peak) plus a Polar H7 chest strap and ECG while walking and jogging on a treadmill.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2019
  • Switching to a vegetarian diet: creatine, carnosine and carnitine stores in women

    Randomized 6-month study with 40 healthy women: continued mixed diet (10), vegetarian diet with placebo (15) or vegetarian diet with 1 g creatine and 0.8 g beta-alanine daily (15). Muscle and blood values as well as VO2max, time to exhaustion and lactate in an incremental cycling test were measured.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2019

2018

  • School-based activity program for girls: counseling plus after-school club over 17 weeks

    Cluster-randomized trial from Michigan State University with 1,543 girls in grades 5 to 8: counseling with the school nurse, individual online feedback and a 90-minute after-school activity club versus usual school offerings. Activity was measured by accelerometer.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2018
  • Early corticosteroid injection after ACL tear: pain, knee function and cartilage markers

    Randomized, double-blind study from the universities of Kentucky and Vanderbilt with 49 athletes aged 14 to 33: corticosteroid (Kenalog, 40 mg) or saline into the knee shortly after an ACL tear. What happened to pain and cartilage markers before surgery?

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2018
  • Mini cycle ergometer at work: breaking up sitting and metabolism in office workers

    Single-arm study at the University of Colorado Boulder with 25 office workers aged 18 to 55 who sit at least 6 hours a day: four weeks of pedalling a DeskCycle for 15 minutes per working hour. Glucose tolerance, VO2max, blood pressure, blood lipids and body composition were measured.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 11/2018
  • Dextrose prolotherapy for shoulder tendon pain: nine-month pain course compared with control injections

    Triple-blind randomized study with 77 adults (aged 19 to 74) with ultrasound-confirmed rotator cuff tendinopathy: 25% dextrose with lidocaine into the tendon insertions, lidocaine alone at those sites, or lidocaine under the skin, each plus physiotherapy.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 08/2018
  • Self-efficacy, action planning or both: effects of brief interventions on adolescents' body fat and activity

    Randomized trial in Polish schools with 1217 adolescents (14 to 18 years): self-efficacy training, action planning, both combined or extended physical activity education. The main outcome was body fat after 14 months, plus activity, planning and self-efficacy.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2018
  • LED light therapy for persistent symptoms after concussion

    Quadruple-blind randomized trial at Boston Children's Hospital: 53 patients aged eleven and older with cognitive symptoms persisting more than four weeks after concussion received 18 LED or placebo sessions over six weeks. Outcomes were ImPACT, executive function tests and symptom scales.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 06/2018
  • Flector patch for minor sports injuries in children: good skin tolerability in an open-label study

    Open-label, single-arm phase 4 study by IBSA with 104 children and adolescents (6–16 years) with minor soft tissue injuries: diclofenac patch twice daily until pain resolved or for up to two weeks. The primary outcome was the skin reaction at the application site.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2018
  • Tau PET in former NFL players with suspected chronic traumatic encephalopathy

    Exploratory imaging study with 30 enrolled men aged 40 to 69: former NFL players with symptoms, former elite athletes without head injuries, and Alzheimer's patients. Can tau and amyloid deposits be told apart with PET?

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2018

2017

2016

  • PRP injection for tendon and muscle injuries: effect on blood growth factors

    Observational study from Stanford University with 25 patients receiving an ultrasound-guided PRP injection into a tendon or muscle. Blood samples before and up to four days after injection were meant to show whether doping-relevant growth factors rise.

    Observational study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2016
  • Pain medication for headache after concussion in children and adolescents

    Open-label randomized pilot study with 80 children and adolescents (aged 8–18) after a first concussion: acetaminophen, ibuprofen, both, or no scheduled medication over 72 hours. Headache days, intensity and return to school were recorded.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 10/2016
  • Progesterone for concussion: pilot study in athletes shows no benefit

    Randomized, triple-blind pilot study with 25 athletes aged 18 to 44: within 24 hours of a concussion they received oral progesterone or placebo for five days. Did the hormone shorten how long symptoms lasted?

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2016
  • Prolotherapy versus sham injections for chronic tennis elbow

    Randomized, triple-blind University of Pittsburgh study with 67 enrolled adults aged 18 to 65: dextrose injection, deep or superficial saline injection at the elbow. Is the effect due to the solution, the needle – or neither?

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2016
  • Investigational drug PF-05175157: single dose with near-identical heart and exercise values to placebo

    Randomized, double-blind phase 1 crossover study with 12 healthy men: a single 600 mg dose of PF-05175157 or placebo, followed by cardiac ultrasound and treadmill cardiopulmonary exercise testing. Outcomes included myocardial strain, OUES, peak VO2 and other exercise measures.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2016
  • Ibuprofen 5% gel versus placebo for acute ankle sprain

    Randomized, triple-blind phase 3 study by Pfizer with 304 participants aged 12 and over: ibuprofen gel twice or three times daily versus placebo gel after a mild to moderate sprain. How much did the gel relieve pain on weight bearing?

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 05/2016
  • Intermittent calf compression after Achilles tendon rupture: thrombosis, tendon healing and function

    Randomized trial at Karolinska University Hospital: 150 adults after surgical repair of an Achilles tendon rupture received two weeks in a plaster cast or an orthosis with daily pneumatic calf compression. Outcomes were thrombosis on ultrasound, a healing marker and calf function at one year.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 03/2016
  • EMG comparison: elastic band versus manual resistance in neck exercises

    Non-randomized lab study by the Sport and Spine Rehab Clinical Research Foundation with 15 healthy active adults and 15 patients with non-radicular neck pain (18–65 years): six neck exercises with Thera-Band and with manual resistance, muscle activity by EMG.

    Training intervention · ClinicalTrials.gov · Registerergebnisse / Registry results · 02/2016
  • Testosterone gel and progressive strength training in older men over one year

    Randomized, quadruple-blind phase 2 trial from the University of Colorado with 167 untrained men aged 60 and over: low or higher testosterone dose or placebo, each with or without strength training three times a week for 52 weeks.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2016
  • Muscle blood flow and muscle protein synthesis in young and older adults

    Physiological phase I study with 62 healthy adults (18 to 40 and 60 to 85 years): 45 minutes of walking at 40% VO2peak or an infusion of sodium nitroprusside, in older adults partly with an amino acid drink. Muscle protein synthesis rate was measured via biopsy.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 01/2016

2015

2014

2013

  • Traumeel ointment and gel versus diclofenac gel for acute ankle sprain

    Randomized, double-blind, multicenter phase 3 trial with 449 enrolled athletes aged 18 to 40 with a fresh lateral ligament injury: Traumeel ointment, Traumeel gel or diclofenac gel, 2 g three times daily for 14 days each. Primary outcomes: pain reduction and daily function on day 7.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 12/2013

2012

2011

  • Exercise-induced asthma and rhinitis in Scottish squad swimmers: screening pilot study

    Cross-sectional study with 97 swimmers (aged 11–23) from Scottish national and district squads: screening with mannitol challenge, sport-specific exercise test, nitric oxide measurement, allergy testing and nasal lavage. The registry reports only exhaled nitric oxide.

    Observational study · ClinicalTrials.gov · Registerergebnisse / Registry results · 09/2011

2010

  • Autologous blood versus corticosteroid injection for tennis elbow

    Randomized study with 60 patients aged 15 to 70: a single injection of autologous blood or methylprednisolone, each with local anesthetic, at the lateral elbow. Pain and symptom stage were assessed at one, four and twelve weeks and at six months.

    Randomized study · ClinicalTrials.gov · Registerergebnisse / Registry results · 07/2010